Endocare Renewal Retinol Comfort Cream is formulated with hydrating and soothing active ingredients that help soothe irritated skin. RetinSphere® Technology stimulates the natural epidermal renewal process, ensuring high tolerability of the treatment. Edafence® protects the skin from external aggressors and strengthens the skin barrier. Tested under dermatological and ophthalmological supervision. Non-comedogenic. Soothes and calms irritated skin. Restores the skin barrier. Anti-wrinkle. Retexturizing. Treatment suitable for all skin types. Directions for use: Apply at night to clean facial skin gradually and as tolerated, according to the Renewal regimen or your prescriber's instructions. Avoid sun exposure or use photoprotection. Avoid direct contact with eyes and mucous membranes. Precautions: Shake before use. External use. Avoid contact with eyes and mucous membranes. Mild stinging and peeling are normal after the first few applications. If irritation persists, discontinue use. A change in color does not affect its effectiveness.