Endocare Renewal Retinol Comfort Cream is formulated with moisturizing and soothing active ingredients that help relieve irritated skin, RetinSphere® Technology stimulates the natural process of epidermal renewal, guaranteeing high tolerability of the treatment, and Edafence® protects the skin from external aggressors and reinforces the barrier cutaneous. Tested under dermatological and ophthalmological control. Non comedogenic. Calms and soothes irritated skin. Restores the skin barrier. Retexturizing anti-wrinkle. Treatment indicated for all skin types. How to use: Apply at night to clean facial skin progressively and as tolerated according to the Renewal regimen or your prescriber's instructions. Avoid sun exposure or use photoprotection. Avoid direct contact with eyes and mucous membranes. Precautions: Shake before use. External use. Avoid contact with eyes and mucous membranes. A slight stinging and peeling is normal in the first applications. In case of continued irritation, suspend the application. A color change does not affect its effectiveness.