Endocare Renewal Retinol Serum, thanks to its anhydrous texture, formulated with RetinSphere® Technology, contains a high concentration of retinoids in microsponges that provide effective epidermal retexturization and renewal. Visibly reduces fine lines and wrinkles and unifies skin texture, thus improving its appearance and radiance. Tested under dermatological supervision. For whom it is indicated: Treatment serum indicated for all skin types. Directions for use: Apply at night to clean facial skin gradually and as tolerated according to the Renewal regimen or instructions from your prescriber. Avoid sun exposure or use photoprotection. Avoid direct contact with eyes and mucous membranes. Precautions: Shake before use. External use. Avoid contact with eyes and mucous membranes. Mild stinging and peeling are normal during the first applications. If irritation persists, discontinue application. A change in color does not affect its effectiveness.